American Airlines on Friday suspended flights to and from Venezuela. American’s pilot union earlier said it told its members to refuse any trips to Venezuela after the State Department told U.S. citizens to leave the country.

American was the last major U.S. carrier to fly to Venezuela. United Airlines and Delta Air Lines ceased service to Venezuela in 2017.

“Do not travel to Venezuela due to crime, civil unrest, poor health infrastructure, and arbitrary arrest and detention of U.S. citizens,” the State Department said in its warning on Tuesday.